How to Use: Adults: 2 pills each time, 3 times daily for mild and middle-degreed patients; increase to 4 pills each time;3 times daily with discretion for serious patients. The limit of daily dosage is 12 pills. The item "Kyushin Heart Tonic (100 Pills), Made in Japan, USA Seller, Fast Shipping" is in sale since Monday, November 21, 2016. This item is in the category "Health & Beauty\Natural & Alternative Remedies\Other Natural Remedies". The seller is "newgreennutrition" and is located in Flushing, New York.This item can be shipped worldwide.